Candidate ranking · Binding & developability assessment

STAPHYLOCOCCAL ENTEROTOXIN B

SEB_01_boltzgen_binder_010

RankedRanked by WeaveRankPatch P01boltzgen61 aa

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Representation

AAGAAAAAAAAAAGDAAGAGAAGAAAGAAAEAGPTAAAVAAGAAAEAGDEEAAKKAWEAAK

61 residues

PRODIGY Kd22th

6.70e-63.40e-10

BindPred log₁₀Kd36th

-4.6-8.2

PRODIGY ΔG22th

-7-12.9

3D-SAP3th

0.1-3.7

Solubility76th

0.40.8

pI97th

10.14.2

WeaveRank3th

-1.52.1

RMSD8th

12.30.2

EpitopeE06

pLDDT0.68

iPTM0.12

pTM0.38

Min interface PAE20.83Å

Quality score0

Filters passed1

Passes filtersNo

WeaveRank

Generator filter: passed

-1.23ensemble rank z · IVTT construct G9

Mean of the member z-scores: structural interface-confidence ensemble (ESMFold2 co-fold), not a lab measurement.

Ensemble members

ESMFold LIS-0.71

ESMFold iPTM-0.76

ESMFold ipSAE (min)-0.59

ESMFold pLDDT (avg)-3.11

ESMFold interface PAE-0.98

Ensemble inputs

cofold ipSAE min0

cofold iPTM0.21

cofold pLDDT avg73.44

cofold LIS0

cofold iface PAE21.05

Display metrics

Protenix ipSAE min0.01

Protenix iPTM0.36

ESMFold pLDDT avg56.33

STAPHYLOCOCCAL ENTEROTOXIN B

STAPHYLOCOCCAL ENTEROTOXIN B

Binder Sequence

vs. Siblings (108 in target)

Epitope Context

Confidence & Quality

Liability

Risk Flags

Interface AA Composition

WeaveRank

Binder Sequence

vs. Siblings (108 in target)

Epitope Context

Confidence & Quality

Liability

Risk Flags

Interface AA Composition

WeaveRank