Interface Design
15 min
Geometric Complementarity in Interface Engineering
Designing steric fit and electrostatic patterns to maximize specificity in therapeutic protein–protein interactions.
Knowledge Center
Knowledge Center
Method notes and reviews from the WeaveSeq Engineering Division: protein binders, hotspot selection, interface design, assay development, and diagnostic translation, built on AffiniBind™.
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FeaturedPipeline Validation
10 min read
Benchmarking Binding-Site Fingerprinting — DB5.5 Validation of the AffiniBind Pipeline
Evaluating the AffiniBind surface fingerprinting pipeline against 223 protein-protein complexes from the Docking Benchmark 5.5 — 87.9% patch hit rate, 96.4% Top-3, and 0.853 AUC on held-out test data.
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