Candidate SEB_01_A · STAPHYLOCOCCAL ENTEROTOXIN B2

SEB_01_All_Generators_pxdesign_binder_001

Top tierPatch P01pxdesign51 aa

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Representation

SKYEKAKELAEKKGEELDKKIKELYAKGKKITSDERRKMAQEVRKEVDKEV

51 residuesBinder chain BTarget chain A

Unified Score100th

0.70.8

Solubility91th

0.60.8

3D-SAP91th

-3.5-1.5

pI0th

4.49.8

Interface Core9th

2747

Interface Rim100th

1524

Scaffold Exposed9th

Scaffold Buried82th

024

Low-Conf. Interface100th

00.7

Interface pLDDT18th

65.492

Scaffold pLDDT27th

5895.3

Lys+Arg Exposed18th

0.61

Mean Exposure100th

0.30.4

Protease Motifs0th

Hydrophobic Patch82th

087

Hydrophobic Interface Patch9th

1529

Pos. Charge Cluster18th

718

Neg. Charge Cluster91th

1015

Max Loop Length91th

Loop Flexibility91th

0.10.2

Buried Unsatisfied36th

Packing Density18th

12.314.5

Min Packing Density100th

Hydrophobic Fraction91th

0.30.5

Charge Asymmetry55th

0.20.5

Exposed Hydrophobic91th

00.1

PRODIGY ΔG55th

-13.6-8.7

PRODIGY Kd55th

iPTM69th

0.10.9

RMSD66th

0.212.2

pLDDT48th

0.60.9

EpitopeE02

Target Contacts (39)

A:THR18A:GLY19A:LEU20A:GLU22A:ASN23A:LYS25A:VAL26A:ASP29A:ASP30A:ASN31A:PHE44A:LEU45A:LYS57A:LEU58A:GLY59A:TYR61A:ASN63A:ARG65A:GLU67A:TYR90+19 more

AF2 pLDDT0.83

iPTM0.73

AF2 pTM0.87

AF2 iPAE8.38Å

AF2-IG-easyYes

Helix fraction0.86

Loop fraction0.14

Rg12.4Å

SEB_01_All_Generators_pxdesign_binder_001

Top tierPatch P01pxdesign51 aa

Loading structure…

Representation

SKYEKAKELAEKKGEELDKKIKELYAKGKKITSDERRKMAQEVRKEVDKEV

51 residuesBinder chain BTarget chain A

Unified Score100th

0.70.8

Solubility91th

0.60.8

3D-SAP91th

-3.5-1.5

pI0th

4.49.8

Interface Core9th

2747

Interface Rim100th

1524

Scaffold Exposed9th

Scaffold Buried82th

024

Low-Conf. Interface100th

00.7

Interface pLDDT18th

65.492

Scaffold pLDDT27th

5895.3

Lys+Arg Exposed18th

0.61

Mean Exposure100th

0.30.4

Protease Motifs0th

Hydrophobic Patch82th

087

Hydrophobic Interface Patch9th

1529

Pos. Charge Cluster18th

718

Neg. Charge Cluster91th

1015

Max Loop Length91th

Loop Flexibility91th

0.10.2

Buried Unsatisfied36th

Packing Density18th

12.314.5

Min Packing Density100th

Hydrophobic Fraction91th

0.30.5

Charge Asymmetry55th

0.20.5

Exposed Hydrophobic91th

00.1

PRODIGY ΔG55th

-13.6-8.7

PRODIGY Kd55th

iPTM69th

0.10.9

RMSD66th

0.212.2

pLDDT48th

0.60.9

EpitopeE02

Target Contacts (39)

A:THR18A:GLY19A:LEU20A:GLU22A:ASN23A:LYS25A:VAL26A:ASP29A:ASP30A:ASN31A:PHE44A:LEU45A:LYS57A:LEU58A:GLY59A:TYR61A:ASN63A:ARG65A:GLU67A:TYR90+19 more

AF2 pLDDT0.83

iPTM0.73

AF2 pTM0.87

AF2 iPAE8.38Å

AF2-IG-easyYes

Helix fraction0.86

Loop fraction0.14

Rg12.4Å

Binder Sequence

vs. Siblings (29 in target)

Epitope Context

AF2 Confidence

Structure

Risk Flags

STAPHYLOCOCCAL ENTEROTOXIN B2

Binder Sequence

vs. Siblings (29 in target)

Epitope Context

AF2 Confidence

Structure

Risk Flags

STAPHYLOCOCCAL ENTEROTOXIN B2